yourlist = [
[125.25,129,128,129],
[124.25,127,130,131],
[126,126,125,124],
[126,124,130,124]
]
def seen(element, _cache=set()):
result = element in _cache
_cache.add(element)
return result
filtered = ([x for x in sublist if not seen(x)] for sublist in yourlist)
filtered = [sublist for sublist in filtered if sublist] # filter out empty lists
